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The gut microbiome also plays a role in precursor metabolism

Freeman LR, Zhang L, Nair A, Dasuri K, Francis J, Fernandez-Kim SO, Bruce-Keller AJ, Keller JN (2013) Obesity increases cerebrocortical reactive oxygen species and impairs brain function

There are disturbing statistics that show that 18% to 44% of dogs worldwide are overweight or obese and this study explains the effect of the supplement

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Its worth bearing in mind that in the case of drug interactions, there may be other factors at play too (not just stomach acidity)