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Poliumoside protects against type 2 diabetes-related osteoporosis by suppressing ferroptosis via activation of the Nrf2/GPX4 pathway

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Diagnostic and therapeutic considerations The revised nomogram should be used for assessment of repeated ingestions that span more than 24 hours

Its aim is to prove that a drug substance which is exposed to light does not undergo unacceptable changes (ICH 1996)resulting not only in loss of activity (degradation) but also in the formation of radicals, energy transfer, or luminescence, which may lead to severe side effects, whose cause could be for example light-induced reaction with endogenous substances (Tonnesen 2004)