Thankfully, there are so many different options for diabetes medications. With both drugs, the most common side effects tend to subside after days, weeks, or months, as the body becomes accustomed to the new medication or a higher dosage
Reduced cravings & food preferences Many patients experience a natural aversion to greasy, sugary, or processed foods, helping them adopt healthier eating habits
Rybelsus (semaglutide) is an oral medication licensed in the UK for the treatment of type 2 diabetes mellitus in adults
The key objective of the SOUL trial was to demonstrate that oral semaglutide 14 mg helps lower the risk of major adverse cardiovascular events (a composite endpoint consisting of cardiovascular death, non-fatal myocardial infarction and non-fatal stroke) compared to placebo, both added to standard of care in patients with type 2 diabetes and ASCVD and/or CKD
Research has examined Semaglutides effects on dopaminergic reward circuit biology , characterising attenuation of substance reward responses and addiction-associated behaviours through GLP-1R-mediated dopamine system modulation in the nucleus accumbens and ventral tegmental area , and neuroprotective effects in neurodegenerative models through GLP-1R-mediated neuroinflammation attenuation, microglial activation modulation, and neuroprotective signalling pathway engagement
