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An RCT in obese patients found that GLP-1 receptor activation by the agonist exenatide reduced brain responses on functional MRI to food cues in appetite- and reward-related brain areas including the insula and amygdala, correlating with reductions in food intake [18]

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Greenhouse-Geisser group (G), time (T), and group x time (G x T) interaction p-levels are reported with univariate treatment p-levels