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in addition, a recently identified 25% increase in the risks of hyperglycaemic crises, acute myocardial infarction, stroke and lower extremity amputation over a 5 year period was most notable in people with diabetes aged 1844 years [275]

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(10) Engel MG, Narayan S, Cui MH, Branch CA, Zhang X, Gandy SE, Ehrlich M, Huffman DM