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Another randomized, double-blind, placebo-controlled trial split their trial group of 159 patients with mild Graves orbitopathy, into two groups

Thyroid dyscrasia may exacerbate arrhythmias, and signs and symptoms should prompt consideration of a thyroid disorder

Brain energy metabolism is tightly regulated and metabolically flexible

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The 60-day washout recommendation leaves a gray zone between 30 and 60 days where serum clearance is likely complete but tissue depot effects remain theoretically possible