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This was characterized by an increase in SCFA-producing bacteria ( Eubacterium hallii group, Dorea , Marvinbryantia , and Papillibacter ) and a decrease in inflammation-associated microbiota ( Prevotella , Veillonella , and Burkholderiales ), along with reduced serum IL-6 levels and a lower ratio of CD4 + memory/naive T cells [76]

long-term use can cause significant adverse effects including kidney problems, hypertension, and non-melanoma skin cancers (Paul 2003

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