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Neuroscience 333(October):277301

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The actions of agouti-related peptide (AgRP) neurons and pro-opiomelanocortin (POMC) neurons in the arcuate nucleus (ARC), the most renowned cell types of the hypothalamus governing homeostatic actions and inducing hunger, were previously understood to be mainly regulated by internal nutritional status or hormones such as leptin or ghrelin [45]