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Semaglutide may be appropriate for certain patients, including those who have failed other weight loss treatments, have blood sugar abnormalities, have a significant amount of weight to lose, or have medical conditions that could improve with weight reduction

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This research was conducted using Truveta, which provides daily updated, complete EHR data from more than 100 million de-identified patients, including labs, images, medication dispense data, and clinician notes linked with claims and SDOH to accelerate research across all diseases, drugs, and devices

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They work by suppressing appetite, slowing gastric emptying, increasing insulin sensitivity, and regulating blood glucose levels