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Regardless of the type of food or another drug concomitant administration, the DPP4i evaluated was able to increase GLP-1 in the studied animals

Quercetin induces the downregulation of ERK1/2, P38 MAPK, and AKT signaling molecules, leading to DNA fragmentation, mitochondrial membrane potential loss, and ROS production, thereby inducing cell apoptosis (144)

This means it mimics the action of the natural GLP-1 hormone that the gut releases after eating

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