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Dopaminergic afferents from the ventral tegmental area (VTA) in the midbrain project largely to the NAc (mesolimbic pathway), while the substantia nigra (SN) pars compacta is the main source of dopamine in the dorsal striatum (nigrostriatal pathway)

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Author contributions Y.S.: study design, study conduct/data collection, writing the manuscript

GLP-1 medications separately slow gastric emptying and may shift lipid metabolism, so the two changes land in the same part of digestion, which is why fat tolerance is worth watching after a cholecystectomy