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1 Studies have shown that GLP-1 RAs have favorable pharmacokinetics and demonstrate anti-inflammatory properties, making them potentially useful beyond glycemic control

Bariatric surgery (like gastric bypass or sleeve gastrectomy) is covered by Medicaid in the majority of states when strict medical criteria are met, typically including a BMI over 40 or BMI over 35 with serious comorbidities

237,238 Several studies using animal models have demonstrated that acute GLP-1 infusion increased heart rate, blood pressure and glucose uptake by the heart, whereas chronic GLP-1R agonism in rodents reduced blood pressure and prevented hypertension

They must also be avoided by women who are planning a pregnancy