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Role of PGC-1alpha in vascular regulation: Implications for atherosclerosis

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In mouse studies with diet-induced obesity, this led to real weight loss, smaller fat cells, less body fat, lower cholesterol, all without cutting food intake or causing obvious side effects

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The subtype JAM-1 is vital in maintaining the integrity of the BBB while the subtype JAM-4 was found by Daneman et al

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doi: 10.3390/ph17010054 28

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