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As body weight decreases, total daily energy expenditure decreases, and the deficit that produced rapid early weight loss narrows

Ailments like anemia and undergone gastrointestinal surgery patients also will not have absorption ability

What the research supports: Semaglutide (GLP-1 medication): Clinical trials show meaningful average weight loss for many people when used with lifestyle support and medical monitoring

In this article, Abba Kastin and colleagues review the known effects of DSIP and argue that further work is needed before it can be considered functional

Additionally, nausea and early satiety may cause patients to rely on easily tolerated but nutritionally limited foods, potentially narrowing dietary diversity