GLP-1 receptor agonists like semaglutide already slow stomach emptying as part of their weight loss mechanism
Numerous endogenous agonists activate the GLP-1R, including several forms of GLP-1, oxyntomodulin and glucagon, and multiple exogenous peptide agonists are approved, or in clinical development, for the treatment of type 2 diabetes and/or obesity 1,2
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The study found that tirzepatide was safe and effective during the fasting month, with improvements in glycemic parameters and weight providing important reassurance for patients considering continuing their treatment during the holy month
Per research from the Blue Cross Blue Shield Association, nearly 6 in 10 will discontinue a GLP-1 before reaching a clinically meaningful health benefit