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evaluated the effects of inhibitors of necroptosis, apoptosis, and ferroptosis (Necrostatin-1, z-VAD-FMK, and Fer-1, accordingly) on primary cultured RGCs suffering RIR injury, with Fer-1 conferring the best efficacy (126)

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NNMT is overexpressed in adipose tissue of obese subjects, and its inhibition has been explored as a strategy to modulate methyl group flux and NAD+ precursor availability

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Conclusions Diabetes and obesity are chronic diseases that are becoming increasingly prevalent worldwide