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Writing in the journal Nature Medicine, a team led by Dr

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Further, nanoparticles were loaded with marine sulphated polysaccharide, known as poly(-amino ester) PPID nanoparticles which have capacity to respond to ROS, and release DOX in a regulated way

The treatment steps were: (1) Colonoscopically get into the small bowel, using fluoroscopy, pass a guidewire (Boston Scientific) through the obstruction, (2) Advance the colonoscope (Olympus) along the guidewire and release the obstruction under the fluoroscopic imaging (Figure)