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PALMITOYL-ETHANOL-AMIDE (PEA) Inclusion: Known for its anti-inflammatory and analgesic properties, PEA adds to the supplement's effectiveness

SAM is involved in hundreds of methylation reactions throughout the body, and the systemic effects of preserving SAM through NNMT inhibition in tissues beyond adipose tissue remain unknown

34 Cellular studies have suggested that ALA may induce nuclear localization of nuclear factor erythroid 2-related factor 2 (NRF2), the most important transcription factor regulating genes that contain the antioxidant response element, thereby modulating peroxisome proliferator-activated receptors-regulated genes

DOI: 10.1016/J.CHEST.2016.11.036 43

ASEAN Journal of Psychiatry