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Van Goudoever JB, Colen T, Wattimena JLD, Huijmans JGM, Carnielli VP, Sauer P 1995 Immediate commencement of amino acid supplementation in preterm infants: effect on serum amino acid concentrations and protein kinetics on the first day of life

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299 Although concerns have been raised about the possibility that SAMe supplementation might increase homocysteine production, a trial in subjects with major depressive disorder found that 8001,600 mg SAMe per day for six weeks did not raise homocysteine levels

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