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Concurrently, DRP-104, the prodrug of DON, has been observed to promote the polarization of tumor-associated macrophages (TAMs) to the M1-TAMs phenotype

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(2) Ipratropium acts as a competitive antagonist at muscarinic receptors in bronchial smooth muscle, inhibiting acetylcholine binding and blocking parasympathetic-mediated bronchoconstriction

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Cells expressing HRP or APEX2 were fixed and washed as described above