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Oral paracetamol can give some pain relief (constipating analgesics, such as codeine, should be avoided) and topical anaesthetics are sometimes used in the short-term, but evidence for their effectiveness over placebo is lacking

Ultimately, international evidence-based guidelines have confirmed these pathological drivers of PCOS (17, 2729)

This makes it ideal for competitive athletes who need that boost, but dont want to have to deal with needle pricks and soreness every day

You've likely reached maintenance when your weight stabilizes over 2 to 3 weeks at the same dose, your appetite-suppressing effects feel sustainable, and side effects are minimal or manageable

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