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Konig SA, Siemes H, Blaker F, Boenigk E, Gross-Selbeck G, Hanefeld F, Haas N, Kohler B, Koelfen W, Korinthenberg R: Severe hepatotoxicity during valproate therapy: an update and report of eight new fatalities
Insulin Signaling in the Whole Spectrum of GH Deficiency
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Crucialmente, este efecto es glucosa-dependiente , lo que significa que la estimulacin de insulina ocurre principalmente cuando los niveles de glucosa estn elevados, reduciendo significativamente el riesgo de hipoglucemia en monoterapia (aunque este riesgo aumenta cuando se combina con insulina o sulfonilureas)