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The doctor may have to adjust the dose based on age, body weight and medical history

By week five, he says, he was "virtually pain-free" and able to do things he had not been able to do for "quite some time"

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Most guidelines recommend discarding after twenty-four to forty-eight hours

So far, bariatric surgery has proven to be the most effective approach to body weight (BW) reduction, as a recent network meta-analysis demonstrated that it was associated with a 17.7% greater BW loss compared to lifestyle intervention/medical therapy 6 , with substantial improvements or remission of T2D, dyslipidemia and hypertension 7