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Oral administration of high-dose vitamin B 12 (1 to 2 mg daily) is considered as effective as intramuscular administration for correcting anemia and neurologic symptoms Despite many studies suggesting oral administration of vitamin B 12 to be easy, effective and less costly than intramuscular administration, debate surrounds the effectiveness of the oral route

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With a weight loss of 15%, there is a remarkable reduction in CKD progression, heart failure outcomes, MASLD, cardiovascular events, cancers, cancer mortality, and overall mortality [4, 5]