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Lifestyle changes are the hardest to make and these patients require support to be successful

The knee angle was confirmed between 125 and 135 using a hand-held goniometer and the hip angle was approximately set at 175

Key areas to watch include: Improved drug formulations with extended-release options Combination therapies involving GLP-1 agonists Personalized treatment plans enhanced by genetic profiling Expansion of GLP-1 applications to other metabolic health conditions Advancements in these areas may lead to better treatment adherence and effectiveness

Were excited to bring these strategies together to help address real-world portfolio challenges in a thoughtful, outcome-oriented way. Important Considerations Unlike the underlying ETFs, BUFX and BUFH do not directly pursue a target outcome strategy