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Their onset can be avoided or the severity reduced to a large extent if dose escalation is performed as indicated in the label, and if, while treatment lasts, a series of well-defined dietary and behavioral recommendations are followed.66 In patients who observe these recommendations, the adverse effects may disappear in a few days or weeks.67 Arguments in favor of GLP-1 receptor agonists for weight control in patients with obesity and inflammatory dermatoses As mentioned earlier, weight loss has a positive effect on the outcome and response to treatments for PsO and HS

Bariatric surgery may be considered for those with BMI 40 kg/m or 35 kg/m with obesity-related complications (with recent guidelines supporting consideration at lower BMI thresholds with metabolic disease)

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