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546,547 Olpasiran demonstrated a dose-dependent reduction in Lp(a) levels, with a single dose of 9 mg or higher reducing Lp(a) concentrations by over 90% for several months (NCT03626662)

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Additionally, "some herbal or 'natural' remedies for constipation, like aloe, cascara, or senna-based products are stimulant-based," says Hamilton, "meaning they work by causing the intestines to contract more forcefully." While these supplements can be effective for short-term relief, Hamilton warns that frequent use can lead to cramping, diarrhea, or dependence

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