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It also reflects the distribution of sulfur and one-carbon metabolism between methionine recycling, methylation and antioxidant production

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DSS-induced colitis in mice elicited pronounced symptoms, including reduced locomotor activity, decreased consumption of food and water, dull and lifeless fur, signs of depression-like behavior, huddling behavior, perianal swelling and congestion, diarrhea, bloody stools, and substantial weight loss

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The peptide's discovery stemmed from research into gastric juice proteins that demonstrated protective effects on gastric mucosa