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The psychological impact of persistent pain should not be underestimated, and addressing the cognitive and emotional components of the pain experience can meaningfully improve outcomes

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This shows up as harder-to-build muscle, increased body fat (especially midsection), slower recovery, lower energy, reduced bone density, and weaker immune function

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Baseline gene expression profiles associated with IGF-I response To evaluate whether gene expression could have a role in predicting response to r-hGH, the relationship between profiles at baseline (treatment-nave patients) and change in serum IGF-I was assessed by rank regression analysis