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Antihistamines are typically the first line of defense in treating a wide range of symptoms because they act as an inverse agonist (receptor blocker) to hinder mediators from binding

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Because theyre generic, they have a lower out-of-pocket cost than the brand-name versions

However, we did not observe significant differences in circulating IGF-1 levels with mAb treatment in older mice, though levels tended to be higher in mAb-treated females, but glucose homeostasis was not adversely affected in either sex, suggesting minimal disruption of the somatotropic axis in this older cohort of mice