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Materials and methods Materials Span 60 and cholesterol were obtained from Agitech for Integrated Scientific Instruments Co., SAE, New Cairo City, Egypt

6-alpha-methylprednisolone (1 mg/kg intraperitoneally, once daily) was given alone which produced a considerable worsening and was completely eliminated with coadministration of BPC 157 10 g/kg intraperitoneally

Rickettsia and their close relatives are obligate to the host cell cytosol, where they parasitize over fifty metabolites 10,11

Important Notice: Retatrutide and Cagrilintide may be subject to prescription requirements, regulatory restrictions, or ongoing clinical evaluation depending on local laws and regulations

CoIP assay Cells were harvested and lysed with RIPA buffer supplemented with protease inhibitor cocktails and phosphatase inhibitor cocktails