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instead they are a precaution stemming from findings in the Saxenda (liraglutide) trials where a small number of participants reported psychiatric symptoms (though these were not significantly different from the placebo group)

Ethics statement The animal study was reviewed and approved by Hebei General Hospital institutional animal care and conducted according to the AAALAC and the IACUC guidelines

The FDA-approved, branded versions of GLP-1 products were so popular that the brand manufacturers were not able to keep up with demand, prompting the FDA to declare a shortage for each of the semaglutide and tirzepatide products over the course of 2022

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