We are also grateful to two anonymous reviewers, whose comments have greatly improved the manuscript
Restored PI3K/Akt signaling and increased GLUT1/GLUT3 expression ( ameliorated memory deficits, reduced amyloid burden, improved gut microbiota composition, reduced pro-inflammatory markers (IL-6, IL-1), and enhanced antioxidative enzymes (SOD, IL-4) (Gu et al., 2021)
Because NAC contains sulfur (which gives it its characteristic, slightly pungent odor), some individuals may experience mild sulfur-tasting burps
Fer-1 treatment might reduce lipid peroxidation to a moderate level which favors axonal fusion, whereas ML162 treatment might not further enhance the already high lipid peroxidation level
"However, when the body is deficient in glutathione and needs much higher levels, food alone may not be enough