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Small molecule erastin can directly and selectively target and inhibit the System X c , and irreversibly bind to and inactivate XCT, leading to continuous disorder of cystine uptake, a decrease in cellular antioxidant capacity, and eventually ROS accumulation and ferroptosis (Sato et al., 2018

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Mizuno S, Yoshikawa N, Seki M, Mikawa T, Imada Y (1988) Microbial production of cis , cis -muconic acid from benzoic acid

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