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Maintenance phase: Once the loading phase is complete, patients transition to maintenance therapy with 1 mg hydroxocobalamin intramuscularly every two to three months for life

Suppression of neuronal apoptosis and glial activation with modulation of Nrf2/Ho-1 and Nf-kb Signaling by Curcumin in Streptozotocin-induced diabetic spinal cord central neuropathy

Stimulates collagen synthesis, accelerates wound healing, and modulates 4000+ genes

J Exp Med 41(4):551560 Santana MS, de Lacerda MVG, Barbosa MdGV, Alecrim WD, Alecrim MdGC (2009) Glucose-6-phosphate dehydrogenase deficiency in an endemic area for malaria in Manaus: a cross-sectional survey in the Brazilian Amazon

It erupted spectacularly in 1995 and has remained active ever since