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For weight management, being overweight alone isnt always enough for insurance companies to cover GLP1 drugs
Not dramatic overnight results, but steady improvement
GLP-1 may nevertheless also directly inhibit glucagon secretion, because -cell-specific GLP-1R KO mice have elevated non-fasting glucagon levels relative to wildtype controls and female -cell-specific GLP-1R KO mice are mildly glucose intolerant with increased secretion of glucagon upon peripheral administration of glucose [607]
For example, liraglutide was first approved in 2010 as Victoza for treatment of diabetes and later approved in 2014 as Saxenda for weight loss
Science evolves
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