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The front and outer portions of the thigh contain adequate subcutaneous tissue for proper medication absorption, and patients can easily see and reach this area without assistance

On April 30, 2026, the FDA proposed excluding semaglutide, tirzepatide, and liraglutide from the 503B outsourcing facility bulks list, finding no clinical need for large-scale compounding of these medications from bulk substances

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The agency said these issues showed bigger problems with Novo Nordisks pharmacovigilance system

Ultimately, deciding whether to pull the trigger on Rybelsus versus sticking with traditional therapies isnt just about immediate cost