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doi: 10.3389/fimmu.2024.1473203 Received 30 July 2024 Accepted 09 September 2024 Published 27 September 2024 Volume 15 - 2024 Edited by Bufu Tang, Fudan University, China Reviewed by Hongquan Wang, Peking University Aerospace School of Clinical Medicine, China Jindong Xie, Sun Yat-sen University Cancer Center (SYSUCC), China Dechao Feng, University College London, United Kingdom Updates Copyright 2024 He, Li, Wu, Liu, Li, Zheng and Lai

The glucagon receptor component is what distinguishes retatrutide it drives energy expenditure at rest, promotes fat oxidation over muscle catabolism, produces dramatic liver fat reduction, and contributes to the osteoarthritis pain relief seen in clinical trials