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By demonstrating protective effects in a ciliopathy model, this study suggests that GLP-1 RAs may confer benefits beyond appetite suppression in patients with genetic obesity syndromes affecting ciliary function, further broadening the mechanistic rationale for targeting this pathway across diverse genetic etiologies of obesity

Researchers tie bile acids to cholangiocarcinoma development

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That is to say that around 5% of the worlds population is obese with a high risk of health complications