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In vitro cellular senescence models (such as senescence models of human fibroblasts, hepatocytes, and nerve cells) are common tools for studying aging mechanisms and interventional drugs

- 5-Amino-1MQ is studied in research models involving NNMT pathway activity, NAD+-adjacent metabolism, adipocyte biology, methylation-related signaling, cellular energy regulation, and body-composition pathway research

Nutr Neurosci

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(Osteoarthritis rabbit model, cartilage repair, inflammation inhibition) Stier E, et al