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Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative lc-ms analysis of therapeutic antibodies in the cerebrospinal fluid

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Abbreviations FOSHU: Foods for Specific Health Use FDA: Foods and Drug Administration HFFs: Health Functional Foods MFDS: Ministry of Food and Drug Safety CAGR: Compound Annual Growth rate NO: Nitric oxide SOD: Superoxide dismutase COX-2: Cyclooxygenase 2 5-LOX: 5-Lipoxygenase iNOS: Inducible nitric oxide synthase HFD: High Fat Diet HRAS: GTPase Harvey rat sarcoma viral oncogene homolog HSP90AA1: Heat shock protein 90-alpha HCT15: Human colon adenocarcinoma cells DPPH: 2,2 -Diphenyl-1-picrylhydrazyl ABTS: 2,2-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) DNA: Deoxyribonucleic acid mRNA: Messenger ribonucleic acid CRISPR: Clustered Regularly Interspaced Short Palindromic Repeats References Martins APdO, Bezerra MdF, Marques Junior S, Brito AFd, Urbano SA, Borba LHF et al (2020) Factors affecting the consumption of organic and functional foods in Brazil