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Upregulation of autophagy-related proteins (including BCL-1, ATG7, ATG5, and LC3-II) in synovial tissues contributes to synovial fibroblast proliferation, resistance to apoptosis, and chronic inflammatory activation

It is not classified as a controlled substance under the Misuse of Drugs Act 1971, but it is also not approved as a medicine or food supplement

Other studies found the drugs can potentially treat brain and mood disorders like Alzheimers, Parkinsons, depression, anxiety, suicide and bipolar disorder

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