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Whats New: ASCO GI 2026 Data on GLP-1 Agents At ASCO GI 2026, several large-scale analyses presented the strongest clinical signals to date linking GLP-1 receptor agonist use with reduced colorectal neoplasia risk

Dempsey reported that many of her patients with gut motility issues are doing well on the low doses of the drug being used, and a mast cell paper reported that reductions in nausea were common

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The drug's primary actions on GLP-1 receptors do not appear to involve effects on the gastrointestinal mucosa that would predispose to bleeding