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[1] Don't purchase over-the-counter B12 supplements without medical guidance, as this can interfere with accurate assessment and may mask underlying conditions

Importantly, treatment of DIO mice with our NNMT inhibitors did not impact food intake, but produced marked reductions in body weight, WAT mass, adipocyte size, and cholesterol levels with negligible toxicity or observable adverse effects

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This bypasses the digestive system, which can be helpful for people with B12 deficiency caused by absorption issues

This, in turn, will aid inflammation and weight loss