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The Weight Loss Numbers The Phase 3 results are why the filing matters

Inhibitor of apoptosis proteins (IAPs) are a family of endogenous caspase inhibitors, with X-linked inhibitor of apoptosis protein (XIAP) responsible for inhibiting caspase-3 and caspase-9 (Obexer and Ausserlechner, 2014)

10.1155/2016/1737185 203 ZhangC.SongY.ChenL.ChenP.YuanM.MengY.et al (2022a)

In Phase 2 trials involving participants with type 2 diabetes, HbA1c improved by up to 2.2%, with 82% of participants reaching HbA1c levels at or below 6.5%

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