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The apoptosome complex activates caspase-9, which cleaves and activates downstream effector caspases such as caspase-3 and caspase-7

The intravenous administration of liposomes loaded with PDE3B siRNA was observed to promote the macrophage anti-inflammatory program, reduce the inflammatory response and synoviocyte infiltration, and attenuate bone and cartilage erosion in CIA mice

Ruscoe JE, Rosario LA, Wang T, Gate L, Arifoglu P, Wolf CR, Henderson CJ, Ronai Z and Tew KD

They indicated that species such as Chlorococcum sp

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