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A novel intronic mutation results in the use of a cryptic splice acceptor site within the coding region of UGT1A1, causing CriglerNajjar syndrome type 1

The frequency of bowel movements may increase or decrease compared to your baseline pattern

GLP-1 agonists may be preferable in some elderly patients due to lower hypoglycemia risk, though GI side effects and potential for weight loss (which can be undesirable in frail elderly patients) require careful consideration