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Glucagon-like peptide-1 (GLP-1) medications, widely known for their effectiveness in promoting weight loss in individuals struggling with obesity and type 2 diabetes, are showing promising new potential benefits beyond metabolic health

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In neuroendocrine models, DSIP influences hormone release dynamics, particularly those linked to circadian and sleep-associated processes [4]

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132 However, therapies for these challenging diseases are limited, because of the lack of effective methods, to enable drugs surpass natural protective hindrances to maintain homeostasis within the brain for preventing the entry of drug molecules to the CNS