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The same study also found that though there were side effects like nausea, diarrhea and vomiting, users were less deterred by side effects if it meant substantial weight loss

The cortisol response to food is also enhanced in obese subjects compared to normal BMI individuals (222)

Furthermore, our study underscores the potential of P188-mediated CSD formulations in augmenting the dissolution rate and bioavailability of poorly soluble drugs by minimizing drug particle size and sustaining drug supersaturation, thereby enhancing the efficacy of sorafenib in treating liver cancer

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& Karlamangla, A