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No diabetic retinopathy at baseline: typically annual exams, with earlier follow-up if high baseline A1c, large early A1c drop, or new symptoms Mild nonproliferative diabetic retinopathy: every six to twelve months, shorter intervals if rapid glucose changes or symptoms appear Moderate nonproliferative retinopathy: every three to six months Severe nonproliferative retinopathy: every two to three months Proliferative diabetic retinopathy or prior macular edema: individualized schedule, often every two to four months when stable, more frequent when starting treatment Starting semaglutide may justify scheduling one additional exam during the first six months in higher-risk patients to catch any early worsening

Then, parties on both sides will begin collecting and exchanging information, which is a process known as discovery

Giraudi et al (206) co-cultured HuH7 and human hepatic stellate cells

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